"The Pharisees also with the Saducees came, and tempting desired Him that He would shew them a sign from heaven. He answered and said unto them, When it is evening, ye say, It will be fair weather: for the sky is red. And in the morning, It will be foul weather today: for the sky is red and lowering. O ye hypocrites, ye can discern the face of the sky; but can ye not discern the signs of the times? A wicked and adulterous generation seeketh after a sign; and there shall no sign be given unto it, but the sign of the prophet Jonas..." Matthew 16:1-4
In essence Jesus was rebuking the religious leaders of the time for having matured in the art of scientific observation, but lacking in spiritual inclination. We see some of the same sickness in our society today. Many people can tell you what is going on in the world around them from a scientific or natural point of view, but when it comes to spiritual matters, they are ignorant.
We have become reliant on our ability to forecast the weather of life by the degree of education we accomplish. We have psychiatrist treating people with drugs without consulting with God in prayer first and the demons that are tormenting some of their patients love the drugs. We have educators at the highest levels of academics forecasting that the students life will be better served if he or she forgets about a God that does not exist. We have presidents denying the Son of God as the only way to the Father. Jesus said (paraphrased) you treat the signs of the times with medicines that don't work and advice that destroys souls, but you can't even see the simple truths of the spiritual life. There will be no sign given this generation, that this generation of unbelievers can understand.
If you are looking for the brilliant minds (secular humanist) of our century to pull us out of our nations troubles, you are not listening to God. They can't. They don't have the spiritual eyes required to make short and long term decisions that acknowledge and honor God. The signs of the times are a little now like they were in Jesus' time. Jesus had come to the world as the Son of God, the Way the Truth and the Life and He was not recognized by His own people. Today Jesus is alive and He has come unto His own again by the indwelling Holy Spirit and He is not recognized by many of His own people.